Eisai Inc. / Andover Site (Research Laboratory)

Location: Andover, Massachusetts, U.S.A. (the Boston suburb)

Study Period：Length of the project is estimated to be 6 continuous months but could be flexible.

Research content：
Dense and large-scale genotype-phenotype data generated by next generation sequencing and high-sensitive biomarker measurement has enabled unprecedented opportunity to characterize genotypic and phenotypic causes & consequences of human variability which will dramatically increase the value of human genomics in drug discovery. Students will work with computational scientists and geneticists in Eisai to develop innovative computational methods to improve detection of genotype-phenotype associations.

Potential projects:
1. Creation of a method to impute missing results from human genetic studies (genomewide association studies).

2. Creation of a method to estimate ethnicity of a human genetic study cohort based on results of an association study.

3. Genetic analysis of Alzhiemer’s disease-related traits and creation/evaluation of method(s) to compare results for different traits.

Expertise:
Student should have experience with informatics and knowledge or strong
interest in human genetics. Knowledge of statistics is also strongly
preferred.

Presentations, etc.：
When the project has been successfully completed, student will be able to participate in the authorship as with researchers on the occasion of their result presentation, e.g. Academic Conferences, Scientific Papers, etc.

Contact:
For further coordination with research laboratory, please contact Dr. Takeshi Nagasu at takeshi.nagasu[at]nifty.ne.jp. (Please replace [at] to @)
The interview test will be conducted by laboratory researcher and/or staff in charge in any way, please note.

 

Thank you.